22948 Rar <95% PROVEN>

The gene provides instructions for making a protein called the retinoic acid receptor alpha, which is a nuclear receptor critical for various biological processes.

: RARA acts as a transcription factor. When it binds to Retinoic Acid (a derivative of Vitamin A), it regulates the expression of genes involved in cell growth, differentiation, and development. 22948 rar

: Understanding this receptor has been a breakthrough in cancer treatment. Patients with APL are often treated with high doses of all-trans retinoic acid (ATRA) , which forces these leukemia cells to mature and die, turning a once-fatal disease into one of the most curable forms of leukemia. The gene provides instructions for making a protein