Bioactive Natural Products: Chemistry And Biology -

: Nitrogen-containing heterocyclic compounds often derived from amino acids. They frequently exhibit potent pharmacological effects, such as the analgesic properties of morphine.

: Assembled from acetate and malonate units via "assembly line" enzymes, producing complex structures like erythromycin. Bioactive Natural Products: Chemistry and Biology

: The largest group of natural products, built from five-carbon isoprene units. Examples include the antimalarial agent artemisinin. potentially revealing new chemotypes.

: Modern research uses metagenomics and gene mining to uncover "silent" biosynthetic gene clusters (BGCs) in microbes, potentially revealing new chemotypes. Bioactive Natural Products: Chemistry and Biology