: The episode opens with a high-stakes heist at a Vatican City museum . A mysterious villain known as the White Rabbit steals the Force Edge , the legendary sword of the demon knight Sparda.
The first episode of varies significantly depending on whether you are watching the 2025 Netflix adaptation or the 2007 original anime . Netflix Series (2025): " Inferno "
: It is later revealed that the girl Dante is escorting is a decoy . The real Patty Lowell is an adult woman who used the child to draw out demonic assassins hired by the billionaire's brothers to secure the fortune for themselves. Devil May Cry Episode 1
: Dante is hired by his agent, Morrison , to protect a young orphan named Patty Lowell .
: After Dante defeats a brother who had been replaced by a demon, the real Patty offers to take care of the orphan, but the child ultimately chooses to stay at the Devil May Cry shop. Video Game (2001): "Mission 1" : The episode opens with a high-stakes heist
: The White Rabbit’s goal is to tear down the barrier between the human and demon realms, which was originally sealed by Sparda using the Force Edge and a magical amulet. Original Anime (2007): " Devil May Cry "
: The heist prompts the U.S. government to involve DARKCOM , an interdimensional security agency led by the religious fanatic Vice President William Baines . They capture an information broker named Enzo Ferino , who provides background on Dante’s past and his family’s tragic history with demons. Netflix Series (2025): " Inferno " : It
The series premiere, titled introduces a darker, more modern take on the demon hunter Dante.