: It binds to and stops the pump, causing sodium to build up inside the cell.
(pronounced WAH-bane ), also known as g-strophanthin , is a potent cardiac glycoside and steroid hormone naturally found in both African plants and mammals. Historically used by African hunters as an arrow poison due to its rapid effect on the heart, it is now primarily used as a research tool for studying cell signaling and, in some countries, as a medication for heart conditions. How it Works: The Na+/K+-ATPase Pump
: Conversely, abnormally high levels of endogenous ouabain are linked to chronic high blood pressure and heart failure.
: High doses have shown an ability to inhibit the growth of certain tumor cells, including thyroid and lung cancers.
: It binds to and stops the pump, causing sodium to build up inside the cell.
(pronounced WAH-bane ), also known as g-strophanthin , is a potent cardiac glycoside and steroid hormone naturally found in both African plants and mammals. Historically used by African hunters as an arrow poison due to its rapid effect on the heart, it is now primarily used as a research tool for studying cell signaling and, in some countries, as a medication for heart conditions. How it Works: The Na+/K+-ATPase Pump
: Conversely, abnormally high levels of endogenous ouabain are linked to chronic high blood pressure and heart failure.
: High doses have shown an ability to inhibit the growth of certain tumor cells, including thyroid and lung cancers.
