This is the most common reaction for substituted quinones. A nucleophile (like an amine, thiol, or alcohol) attacks the double bond.
Substituted quinones are some of the most versatile electrophiles in organic chemistry. Because the quinone core is electron-deficient, their reactivity is largely governed by the nature and position of the substituents ( -groups) attached to the ring. 1. Nucleophilic Conjugate Addition (Michael Addition) reactions of substituted quinones
) on the quinone accelerate the reaction by lowering the LUMO energy. This is the most common reaction for substituted quinones
If the quinone is unsymmetrically substituted, the nucleophile typically attacks the less hindered carbon or the carbon with the lowest electron density. reactions of substituted quinones
